Kaiser Raman units installed worldwide
In the traditional off-line quality control, samples are taken at various process stages and transported to a quality lab for analysis. It may take hours until the results are available, resulting in a delay, making result-based process control impossible. In a PAT-based approach the pharmaceutical manufacturing process and the analytical instrument, such as a spectrometer, acquire in-line measurement results in real time. This real-time data can improve both process control and product quality.
We can help you achieve advanced process control through in-line measurement of your critical quality parameters. You can get the analysis results in seconds instead of hours. From time consuming sample analysis to real-time monitoring of critical process parameters or critical quality attributes. With our optical technologies, such as Raman and UV spectroscopy, you can monitor and control the concentration or composition of your process media or final product in real time. Your benefits are:
improved process control leading to optimized production and increased yield and quality
elimination of contamination risks and time savings thanks to in-line process monitoring without the need for sampling
complete packaged solutions for upstream and downstream process
simplified scale-up with probes for all scales and technologies (i.e. glass, stainless steel, single-use plastic)
With inline spectrometers a measurement frequency in the range of seconds can be achieved, thus enabling real-time advanced process control (APC) in pharmaceutical manufacturing. The move to process analytical technology (PAT) can help you develop processes that generate higher quality products and improve efficiency through increased automation, reduction in cycle times and uninterrupted batch/continuous processing.
fermentation batches until ROI of a single channel Kaiser Raman Rxn system
lower maintenance costs of a Raman measurement compared to a chromatography system
less time spent calibrating one UV sensor with Easycal